Research Articles Issue 1 · 2020 · pp. 125–131 · Issue page

BIOCHEMICAL PARAMETERS IN ACUTE PANCREATITIS

GE
MA
FL
LA
VA
CO
VA
1 County Emergency Hospital of Ploiesti, Romania, ( corresponding author)
2 “Dr Carol D avila” Central Emergency University Military Hospital, Bucharest, Romania ; “Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania
3 “Dr Carol Davila” Central Emergency University Military Hospital, Bucharest, Romania
4 “Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania
5 “Dr Carol Davila” Central Emergency University Military Hospital, Bucharest, Romania
6 Fundeni Clinical Institute, Bucharest, Romani a; “Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania
7 “Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania
Corresponding author: [email protected]
Received 04 January 2020
Revised No
Accepted 25 February 2020
Available Online 15 March 2020
BACKGROUND ACUTE PANCREATITIS REPRESENT AN INFLAMMATORY DISEASE WITH DIFFERENT GRADES OF SEVERITY, RANGING FROM MILD TO SEVERE PRESENTATIONS.THERE ARE A LOT OF BIOMARKERS USED IN DIAGNOSIS AND PROGNOSIS OF ACUTE PANCREATITIS. OUR AIM WAS TO EVALUATE DIFFERENT BIOCHEMICAL PARAMETERS AT TWO MOMENTS OF PANCREATITIS:ADMISSION AND DISCHARGE. METHOD:WE INCLUDED 100 PATIENTS.ALL THE PATIENTS WERE EVALUATED AT ADMISSION AND DISCHARGE.DATA ON BIOCHEMICAL PARAMETERS SUCH AS AMYLASE, LYPASE WERE COLLECTED. RESULTS:WE HAVE OBTAINED SIMILAR RESULTS LIKE IN THE STUDIES FROM LITERATURE REGARDING DIAGNOSIS OF ACUTE PANCREATITIS USING AMYLASE, LIPASE, LEUKOCYTES, BILIRUBIN, LACTATE DEHIDROGENASE.
AMYLASE LIPASE ACUTE PANCREATITIS
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[1]
Lempinem M, Puolakkainen, E. Kemppainen .Clinical value of severity markers in acute pancreatitis. Scandinavian Journal of Surgery 2005, 94: 118–123.
[2]
Dervenis CG: Staging acute pancreatitis: where are we now? Pancreatology 2001;1:201–206
[3]
Forsmark Chris E., Swaroop Santhi Vege,Wilcox Mel C ., Acute pancreatitis. The New England Journal of Medicine, 2016;375:1972-81
[4]
Yadav D, Lowenfels AB . The epidemiology of pancreatiti s and pancreatic cancer. Gastroenterology 2013; 144: 1252-61
[5]
Coté GA, Yadav D, Slivka A, et al . Alcohol and smoking as risk factors in an epidemiology study of patients with chronic pancreatitis. Clin Gastroenterol Hepatol 2011; 9: 266 -73
[6]
Ismaila O., Bhayanab V ., Lipase or amylase for the diagnosis of acute pancreatitis? Clinical Biochemistry 2017,50 :1275–1280
[7]
N.W. Tietz, A. Burlina, W. Gerhardt, W. Junge, P. Malfertheiner, T. Murai, M. Otte, W. Stein, M. Gerber, G. Klein, et al ., Multicenter evalua tion of a specific pancreatic isoamylaseassay basedonadouble monoclonal-antibody technique,Clin.Chem.1988,34 (10) :2096–2102
[8]
M.Y. Moridani, I.L. Bromberg , Lipase and pancreatic amylase versus total amylase as biomarkers of pancreatitis: an analytical investigation, Clin. Biochem. 2003,36 (1) :31–33
[9]
R.W. Yang, Z.X. Shao, Y.Y. Chen, Z. Yin, W.J. Wang , Lipase and pancreatic amylase activities in diagnosis of acute pancreatitis in patients with hyperamylasemia, Hepatobiliary Pancreat. Dis. Int. 4 (4) (2005) 600–603
[10]
J.W.Y. Chang, C.H. Chung , Diagnosing acute pancreatitis: amylase or lipase? Hong Kong J. Emerg. Med. 18 (2011) 20–24
[11]
D. Gomez, A. Addison, A. De Rosa, A. Brooks, I.C. Cameron , Retrospective study of patients with acute pancreatitis: is serum amylase still required? BMJ Open 2012, 2 (5).
[12]
H.S. Batra, A. Kumar, T.K. Saha, P. Misra, V. Ambade , Comparative study of serum amylase and lipase in acute pancreatitis patients, Indian J. Clin. Biochem.2015, 30 (2) :230 –233
[13]
R.C. Smith, J. Southwell -Keely, D. Chesher , Should serum pancreatic lipase replace serum amylase as a biomarker of acute pancreatitis? ANZ J. Surg. 2005; 75 (6) :399–404
[14]
G. Yin, X. Cang, G. Yu, G. Hu, J. Ni, J. Xiong, Y. Hu, M. Xing, C. Chen, Y. Huang, M. Tang, Y. Zhao, G. Cheng, R. Wan, S. Wang, X. Wang, Different clinical presentations of hyperlipidemic acute pancreatitis: a retrospective study, Pancreas ,2015,44 (7) :1105–1110
[15]
W. Tsuang, U. Navaneethan, L. Ruiz, J.B. Palascak, A. Gelrud, Hypertriglyceridemic pancreatitis: presentation and management, Am. J. Gastroenterol.2009, 104 (4) :984-991
[16]
S.L. Orebaugh, Normal amylase levels in the presentation of acute pancreatitis, Am. J. Emerg. Med. 1994,12 (1) : 21–24.
[17]
S.J. Spechler, J.W. Dalton, A.H. Robbins, S.G. Gerzof, J.S. Stern, W.C. Johnson, D.C. Nabseth , E.M. Schimmel, Prevalence of normal serum amylase levels in patients with acute alcoholic pancreatitis, Dig. Dis. Sci.1983, 28 (10) : 865–869.