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Research Articles Supplement 3 · 2014 · pp. 66–72 · Issue page

MANAGEMENT OF OCULAR CICATRICIAL PEMPHIGOID

CO
Corina Ioana BUTEA-SIMIONESCU. Speranta SCHMITZER1
SP
Speranta SCHMITZER2
1 MD, PhD student, OFTALMESTET Clinic Bucharest
2 MD, PhD, OFTALMESTET Clinic Bucharest
Accepted 27 March 2026
Available Online 15 December 2014
Abstract
THE OCULAR CICATRICIAL PEMPHIGOID BELONGS TO A FAMILY OF CHRONICALLY PROGRESSIVE AUTOIMMUNE DISORDERS, PREDOMINANTLY AFFECTING MUCOUS MEMBRANES. THE KEY FEATURE IS THE CHRONICALLY ACTIVE CONJUNCTIVAL INFLAMMATION WITH CONSECUTIVE FIBROSIS, LEADING TO LOSS OF VISION. UNFORTUNATELY, THE EARLY LESIONS ARE SUBTLE AND HARD TO IDENTIFY, MANY PATIENTS BEING TREATED FOR CHRONIC CONJUNCTIVITIS FOR YEARS. THE TREATMENT IS GENERAL AND LOCAL, MEDICAL AND SURGICAL, CONDUCTED BY BOTH THE OPHTHALMOLOGIST AND THE DERMATOLOGIST. MULTIDISCIPLINARY APPROACH AND EARLY DIAGNOSIS ARE THE KEYS TO PREVENTING SERIOUS COMPLICATIONS.
Keywords
PEMPHIGOID OCULAR MANAGEMENT
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References
[1]
Ahmed AR, Foster CS, Zaltas M , et al: Associatio n of DQw7 (DQb1 –0301) with ocular cicatricial pemphigoid. Proc Natl Acad Sci USA 1991; 88:11579–11582
[2]
Albert&Jakobiec’s Principles and Practice of Ophthalmology 3 rd ed, Saunders-Elsevier 2008, vol 1, chapter 46
[3]
Chang JH, McCluskey PJ . Ocular cicatricial pe mphigoid: manifestations and management.Curr Allergy Asthma Rep 2005;5:333–8
[4]
Douglas S. Holsclaw “Ocular Cicatricial Pemphigoid” International Ophthalmology Clinics, 1998, vol 38, Issue 4, 89-106
[5]
Elder MJ, Lightman S, Dart JK: Role of cyclophosphamide and high dose steroid in ocular cicatricial pemphigoid. Br J Ophthalmol 1995; 79:246-264
[6]
Harrisons’s Principles of Internal Medicine 17th ed, 2008, McGraw-Hill, page 340
[7]
Heiligenhans A, Shore JW, Rubin PA, Foster CS . Long -term results of mucous membrane grafting in ocular cicatricial pemphigoid. Ophthalmology. 1993;100:1283
[8]
Hirst LW, Werblin T, Novak M , et al: Druginduced cicatrizing conjunctivitis simulating ocular pemphigoid. Cornea 1982; 1:121.
[9]
Laforest C, Huilgol SC, Casson R , et al. Autoimmune bullous d iseases: ocular manifestations and management. Drugs 2005;65:1767–79.
[10]
Myron Yanoff&Jay S.Duker Ophthalmology 4th ed, Saunders-Elsevier 2013, section 4, chapter 4.10
[11]
Wright P: Cicatrizing conjunctivitis. Trans Ophthalmol Soc UK 1986; 105:1.