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Research Articles Issue 1 · 2021 · pp. 27–38 · Issue page

THE ROLE OF THE VISUAL EVOKED POTENTIALS IN DIAGNOSING AND MONITORING PITUITARY ADENOMAS

MI
Mihaela POPESCU1
MA
Mara CARSOTE2
IU
Iulian Alin Silviu POPESCU3
AN
Andrei COSTACHE4
AL
Alice GHENEA5
AD
Adriana TURCULEANU6
CR
Cristina Elena SINGER7
OA
Oana IANA8
AN
Anca UNGUREANU9
1 Lecturer, Ph.D., The University of Medicine and Pharmacy Craiova, Faculty of Medicine, Departament of Endocrinology
2 Lecturer, Ph.D., The University of Medicine and Pharmacy Carol Davila, Bucharest, Faculty of Medicine, Departament of Endocrinology, National Institute of Endocrinology "C.I.Parhon"
3 Lecturer, Ph.D., The University of Medicine and Pharmacy Craiova, Faculty of Medicine, Departament of Internal Medicine
4 Assistant professor, The University of Medicine and Pharmacy Craiova, Faculty of Medicine, Departament of Biophysics
5 Lecturer, Ph.D., The University of Medicine andPharmacy Craiova, Faculty of Medicine, Departament of Bacteriology-Virology- Parasitology
6 Professor, Ph.D., The University of Medicine and Pharmacy Craiova, Faculty of Medicine, Departament of Bacteriology-Virology- Parasitology
7 Lecturer, Ph.D., The University of Medicine and Pharmacy Craiova, Faculty of Medicine, 2nd Pediatric Clinic, Emergency County Hospital in Craiova
8 C.I. Parhon National Institute of Endocrinology, Bucharest, Romania
9 Assistant Professor, Ph.D., The University of Medicine and Pharmacy Craiova, Faculty of Medicine, Departament of Bacteriology-Virology- Parasitology
Corresponding author: [email protected]
DOI https://doi.org/10.38173/RST.2021.21.1.3:27-38
Received 27 November 2020
Revised 11 January 2021
Accepted 28 January 2021
Available Online 15 March 2021
Abstract
THE VISUAL EVOKED POTENTIALS (VEP) IS A NON -INVASIVE AND REPETITIVE TEST THA T CAN EVALUATE THE EVOLUTION OF A DISORDER OF THE OPTIC PATH. THE AIM OF THIS STUDY WAS TO EVALUATE THE DIAGNOSTIC VALUE OF VEP IN THE EXPLORATION OF THE OPTIC CHIASM SYNDROME IN THE COMPRESSIVE SELLAR CONDITIONS. WE PERFORMED THE ELECTROPHYSIOLOGIC EXAMINATION (VEP) AND OPHTHALMOLOGIC EXAMINATION (VISUAL ACUITY, VISUAL FIELD, FO OPTIC FUNDUS) IN A GROUP OF 51 PITUITARY ADENOMAS PATIENTS AND A 90 HEALTHY SUBJECTS CONTROL GROUP, OF A TOTAL OF 114 STUDIED PITUITARY ADENOMAS. WE NOTED AN INCREASE IN THE LATENCY OF THE P1 00 WAVE THAT STATISTICALLY CORRELATES WITH THE VISUAL FIELD MODIFICATION. THE ADENOMA INDUCED CHANGES WERE BETTER EXPRESSED IN THE HALF FIELD STIMULATIONS (THF, NHF) – WE RECORDED A SIGNIFICANT GREATER I NVOLVEMENT IN THE TEMPORAL FIELD COMPARED TO THE NASA L FIELD.VEP HAVE A GREATER DIAGNOSTIC VALUE COMPARE TO THAT OF THE VISUAL FIELD IN REVEALING THE OPTIC CHIASM COMPRESSION (76.5% VS. 68.6%). THEY CONFIRM THE VISUAL DEFICIT SHOWED BY THE PERIMETRY AND PE RFECTLY REVEAL THE OPTIC PATHS’ INVOLVEMEN T. IN CONCLUSION VEP IS AN INVESTIGATION OF GREAT VALUE IN EVALUATING THE PITUITARY ADENOMA REVEALING FUNCTIONAL ALTERATIONS PRIOR TO THE CLINICAL FEATURES.
Keywords
PITUITARY ADENOMAS VISUAL EVOKED POTENTIALS P100 WAVE HALF FIELD
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