Research Articles Issue 1 · 2019 · pp. 230–238 · Issue page

ALTERATION OF SEROTONIN POSITIVE CELLS IN COLONIC MUCOSA OF PATIENTS WITH INFLAMMATORY BOWEL DISEASE

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1 Fundeni Clinical Institute, Bucharest, Romania
2 Fundeni Clinical Institute, Bucharest, Romania; “Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania
3 Fundeni Clinical Institute, Bucharest, Romania; “Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania
4 Fundeni Clinical Institute, Bucharest, Romania
5 Fundeni Clinical Institute, Bucharest, Romania
6 Fundeni Clinical Institute, Bucharest, Romania
7 Fundeni Clinical Institute, Bucharest, Romania; “Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania
8 Fundeni Clinical Institute, Bucharest, Romania; “Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania
Accepted 29 March 2026
Available Online 15 March 2019
ENDOCRINE CELLS INFLAMMATORY BOWEL DISEASE SEROTONINE
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[1]
Magdy El -Salhy, Tefera Solomon, TrygveHausken, Odd Helge Gilja, Jan Gunnar Hatlebakk, “Gastrointestinal neuroendocrine peptides/amines in inflammatory bowel disease”, World Journal of Gastroenterol 23(28) 2017: 5068-5085, doi: 10.3748/wjg.v23.i28.5068
[2]
Ashok R., Gunawardene ,Bernard M. Corfe, Carolyn A. Staton ,” Clasiffication and function of the enteroendocrine cells of the lower gastrointestinal tract”, International Journal of Experimental Pathology 92 (2011): 219–231,doi: 10.1111/j.1365-2613.2011.00767
[3]
Rindi G, Leiter AB, Kopin AS, Bordi C, Solcia E., “The "normal" endocrine cell of the gut: changing concepts and new evidences”, Annals of the New York Academy of Science,. 1014(2004):1-12 doi:10.1196/annals.1294.001
[4]
Moran GW, Pennock J, McLaughlin JT ,” Enteroendocrine cells in terminal ileal Crohn's disease”, Journal of Crohns andColitis, 6(9) 2012:871-80,doi: 10.1016/j.crohns.2012.01.013.
[5]
Khan WI, Ghia JE. “Gut hormones: emerging role in immune activation and inflammation”, Clinical and Experimental Immunology,161(1) 2010:19-27, doi:10.1111/j.1365-2249.2010.04150.
[6]
Moran GW, Leslie FC, McLaughlin JT, “Crohn's disease affecting the small bowel is associated with reduced appetite and elevated levels of circulating gut peptides”, Clinical Nutrition, 32(3) 2013 :404 - 411, doi: 10.1016/j.clnu.2012.08.024.
[7]
Costedio MM, Hyman N, Mawe GM,” Serotonin and its role in colonic function and in gastrointestinal disorders”, Diseases of the Colon and Rectum,50(3) 2007:276-388
[8]
Li Z., Chalazonitis A., Huang Y. -Y., Mann J. J., Margolis K. G., Yang Q. M., Kim D. O., Côté F., Mallet J., Gershon M. D. ,” Essential roles of enteric neuronal serotonin in gastrointestinal motility and the development/survival of enteric dopaminergic neurons” , Journal of Neuroscience, 31(2011), 8998–9009 , doi: 10.1523/JNEUROSCI.0203-11.2011
[9]
M. El SAlhi, A.Danielsson, R.Stenling, L.Grimelius,” Colonic endocrine cells in inflammatory bowel disease”, Journal of Internal Medicine (242 )1997: 413–419
[10]
Magro F, Vieira-Coelho MA, Fraga S, Serrao MP, Veloso FT, Ribeiro T, and Soares-da-Silva P,” Impaired synthesis or cellular storage of norepinephrine, dopamine, and 5 -hydroxytryptamine in human inflammatory bowel disease”,Digestive Diseases and Siences, (47)2002: 216–224.
[11]
Coates, Matthew D. et al., “Molecular defects in mucosal serotonin content and decreased serotonin reuptake transporter in ulcerative colitis and irritable bowel syndrome”,Gastroenterology, 126(7) 2004 : 1657 – 1664, doi:10.1053/j.gastro.2004.03.013