CONTRIBUTION OF NON-VIRAL RISK FACTORS TO DEVELOPMENT OF HEPATOCELLULAR CARCINOMA
Received
15 March 2020
Revised
9 April 2020
Accepted
26 April 2020
Available Online
02 June 2020
Abstract
THE HE PATOCELLULAR CARCINO MA IS ONE OF FREQUENTLY TYPES OF THE PRIMARY LIVER CANCER IN ADULTS AND IS THE MAIN CAUSE OF DEATH IN PATIENTS WITH LIVER CIRRHOSIS. THE MAJOR RISK FACTOR FOR LIVER CANCER IS CHRONIC INFECTION WITH HEPATITIS B VIRUS (HBV) OR HEPATITIS C VIRUS (HCV). THE R ISK OF DEVELOPEMENT OF THE LIVER CANCER IS INCREASED IN THE PATIENTS WITH CIRRHOSIS. ALSO, NON -VIRAL FACTORS SUCH AS OBESITY, DIABETES MELLITUS, ALCOHOL CONSUMPTION AND/OR NON -ALCOHOLIC FATTY LIVER DISEASE (NAFD) WAS IMPLICATED IN THE DEVELOPMENT OF HEPATOCELLULAR CARCINOMA.
Keywords
HEPATOCELLULAR CARCINOMA
HEPATIC VIRUS
NON-VIRAL FACTORS
Full Text
The body of this article is intentionally hidden on the public page. Please use the PDF reader or the PDF download for the complete text.
References
[1]
Turati F, Galeone C, Rota M, Pelucchi C, Negri E, Bagnardi V, et al., Alcohol and liver cancer: a systematic review and meta-analysis of prospective studies, Annals of Oncology, 2014;25:1526–1535.
[2]
Torres DM and Harrison SA , Nonalcoholic steatohepatitis and noncirrhotic hepatocellular carcinoma: fertile soil, Seminars in Liver Disease, 32: 30-38, 2012.
[3]
Yasui k, Hashimoto E., Komorizone, Koikak, Arii S et al., Characteristics of patients with nonalcoholic steatohepatitis who develop hepatocellular carcinoma , Clinical Gastroenterology and Hepatology, 2011, 9, 428-33.
[4]
Takuma Y and Nouso K, Nonalcoholic steatohepatitis-associated hepatocellular carcinoma: our case series and literature review. World Journal of Gastroenterology, 16: 1436-1441, 2010.
[5]
Polesel J., Zucchetto A, Montella M, Dal Maso L, Crispo A et al. The impact of obesity and diabetes mellitus on the risk of hepatocellular carcinoma, Ann Oncol 2009; 20: 353-357.
[6]
Stickel F., Alcoholic cirrhosis and hepatocellular carcinoma, Advances in Experimental Medicine and Biology, 2015;815:113–130.
[7]
El-Serag HB, Rudolph KL , Hepatocellular carcinoma epidemiology and molecular carcinogenesis , Gastroenterology 2007, 132, 2557-76;
[8]
Mittal S., El-Serog HB., Epidemiology of hepatocellular carcinom a consider the population , Journal of Clinical Gastroenterology 2013, 47 Suppl S2-6;
[9]
De Lope CR, Tremosini S, Forner A, Reig M and Bruix J: Management of HCC, Journal of Hepatology 56, (Suppl 1): S75-S87, 2012;
[10]
Dyal HK, Agu ilor M, Bartos G., Hoet EW, Bhuke t T., Liu B, Cheung R, Wong RJ., Diabetes mellitus increases risk of hepatocelular carcinoma in chronic hepatitis C virus patients: a systematic review, Digestive Disease and Sciences, 2016, 61, 636-45;
[11]
Kamel IR, Blu emke DA., Imaging evaluation of hepatoc ellular carcinoma, Journal of Vascular and Interventional Radiology, 2002;
[12]
Tabor E., Hepatocellular carcinoma: global epidemiology . Digestive and Liver Dis ease, 2001; 33; 115-117;
[13]
Manal A Hamed, Sanaa A Ali, World Journal of Hepatology 2013, June 27, 5 (6): 311-322;
[14]
Lee TY, Wu JC, Yu SH, Lin JT, Wu MS, Wu CY ., The occurrence of hepatocellular carcinoma in different risk stratifications of clinically non -cirrhotic non-alcoholic fatty liver disea se, International Journal of Cancer, 2017, https://doi.org/10.1002/ijc.30784.