REIRRADIATION FOR UNOPERATED RECTAL CANCER AFTER PRIOR PELVIC RADIATION THERAPY- A CASE REPORT
Corresponding author:
[email protected]
Accepted
28 March 2026
Available Online
15 June 2018
Abstract
INTRODUCTION: REGARDING PELVIC RECURRENCE OF UNOPERATED COLORECTAL CANCER,
REIRRADIATION MAY BE AN OPTION FOR PATIENTS WHO STILL REFUSE SURGERY. COMORBIDITIES
LIKE HIGH BODY-MASS-INDEX AND DIABETES HAS BEEN PROVEN TO BE UNFAVORABLE PROGNOSTIC FACTORS FOR PATIENTS WITH RECTAL CANCER. THE REPORT DESCRIBES CASE DESCRIPTION: A 52 YEAR-OLD MAN KNOWN WITH TYPE 2 DIABETES MELLITUS AND DIAGNOSED IN 2012 WITH LOCALLY ADVANCED RECTAL ADENOCARCINOMA WHICH UNDERWENT NEOADJUVANT CHEMORADIOTHERAPY THAT REFUSED SURGERY. THE PATIENT ALSO REFUSED CHEMOTHERAPY REGIMENS, UNDERGOING ONLY CAPECITABINE SINGLE-AGENT THERAPY. FOLLOW-UP CT SCAN AND COLONOSCOPY IDENTIFIED LOCAL PROGRESSION AND, DUE TO PATIENT’S SURGERY REFUSAL, REIRRADIATION AND CONCURRENT CAPECITABINE BASED CHEMOTHERAPY WAS ADMINISTERED. REIRRADIATION WAS PERFORMED USING THE IMRT TECHNIQUE AND A HYPOFRACTIONATED RADIOTHERAPY REGIMEN. AT FOLLOW-UP CT SCAN A REDUCTION OF THE TUMORAL MASS WAS OBSERVED, WITH NO SIGNS OF METASTATIC DISEASE.
CONCLUSION: THIS CASE REPORT SUGGESTS THAT, IN VERY CAREFULLY SELECTED RECTAL
CANCER PATIENTS, PELVIC RE-REIRRADIATION MIGHT BE AN OPTION FOR THOSE WHO REFUSE
SURGERY.
Keywords
CANCER
RECTUM
RADIOTHERAPY
CHEMOTHERAPY
REIRRADIATION
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