PHARMACOLOGICAL AND INTERDISCIPLINARY THERAPEUTIC APPROACH OF A PATIENT WITH CARDIAC DISEASE, SEPSIS AND CHRONIC KIDNEY DISEASE

CHRONIC KIDNEY DISEASE (CKD) IS A PATHOLOGY THAT CAN LEAD TO SLOW LOSS OF NEPHRONS AND RENAL FUNC TION, WITH THE ONSET OF TERMINAL CKD. THE PATHOPHYSIOLOGICAL CHANGES ARE COMPLEX, AND THE ASSOCIATION, ADVERSE, WI TH A LARGE CARDIO -VASCULAR PATHOLOGY, CAN LEA D TO THE DEVELOPMENT OF SEPSIS LATER WITH THE RAPID DECLINE OF RENAL FUNCTION. THE CAS E OF A MALE PATIENT WITH KNOWN C ARDIAC PATHOLOGY, RECENTLY DISCHARGED FROM THE CARDIOLOGY CLINIC, WHO PRESENTS AT THE ER (EMERGENCY ROOM), WITH A VERY SERIOUS G ENERAL CONDITION, WITH RESPIRATORY PATHOLOGY, DYSPNEA WITH ORTHO PNEA, OEDEMA OF THE LOWER LIMBS, PALE TEGUMENTS, SWEAT, BILATERA L SUCCESSIVE RALES, REASONS FOR BEING ADMITTED TO THE CARDIOLOGY SECTION, FALL INTO THIS CATEGORY. AFTER MULTIPLE CLINIC-PARACLINICAL INVESTIGATIONS WERE PERFORMED IN THE CLINIC, THE GENERAL C ONDITION OF THE PATIENT WORSENED AFTER APPROXIMATELY 10 DAYS, WH ICH IS WHY HE IS TRANSFERRED TO THE I NTENSIVE CARE CLINIC, WHERE FURTHER INVESTIGA TIONS ARE CARRIED OUT, T REATING THE FACTORS THA T HAVE WORSENED THE PATIENT'S CONDITION, INCLUDING TREATMENT OF ACUTE CKD AND CARRYING OUT THER APY FOR RENAL FUNCTION REPLACEMENT BY HEMODIALYSIS (HD). HEMODIALYSIS WAS A USEFUL AND LIFE-SAVING THERAPEUTIC MEASURE, CHRONIC KIDNEY DISEASE, ASSOCIATED WITH A SERIOUS CARDIAC PATHOLOGY, FAVOURING THE ONSET OF SEPSIS.

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