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Research Articles Issue 2 · 2020 · pp. 121–127 · Issue page

INFLAMMATORY BOWEL DISEASE AND SEROLOGIC MARKERS OF INFLAMMATION

AN
Andra Consuela IONESCU1
LA
Laura Elena GAMAN2
AL
Alina VASILESCU3
VA
Valeriu ATANASIU4
LU
Lucian IONESCU5
MI
Mihai Mircea DICULESCU6
1 MD, Fundeni Clinical Institute, Gastroenterology Department, Bucharest, Romania
2 “Carol Davila” University of Medicine and Pharmacy, Department of Biochemistry, Bucharest, Romania
3 International Centre of Biodynamics, Bucharest, Romania
4 “Carol Davila” University of Medicine and Pharmacy, Department of Biochemistry, Bucharest, Romania
5 “Academician Stefan Milcu” Medical Center for Diagnosis and Outpatient Treatment, Bucharest, Romania
6 Prof. PhD, Fundeni Clinical Institute, Department of Gastroenterology and Hepatology, Bucharest, Romania
Corresponding author: [email protected]
DOI https://doi.org/10.38173/RST.2020.20.2.11:121-127
Received 14 September 2020
Revised 29 September 2020
Accepted 03 October 2020
Available Online 15 November 2020
Abstract
INFLAMMATORY BOWEL DISEASES, CROHN DISEASE AND ULCERATIVE COLITIS, CAUSE CHRONIC INFLAMMATION OF THE DIGESTIVE TRACT, TRIGGERED BY A COMPLEX INTERACTION OF ENVIRONMENTAL FACTORS, IMMUNE, BACTERIAL, GENETIC FACTORS. MANY MARKERS HAVE BEEN STUDIED AS INDICATORS OF INTESTINAL INFLAMMATION. SERUM C - REACTIVE PROTEIN, ERYTHROCYTE SEDIMENTATION RATE, LEUKOCYTES, SERUM LYSOZYME ARE NON-INVASIVE, EASY TO REPRODUCT AND ACCESSIBLE BIOMARKERS OF INFLAMMATION IN IBD. THIS ARTICLE AIMS TO HIGHLIGHT THEIR ROLE IN EXPRESSING THE INTESTINAL INFLAMMATION, IN ESTABLISHING THE DEGREE OF DISEASE ACTIVITY, IN MONITORING THE DISEASE , IN PREDICTING RELAPSES AND IN MONITORING THE THERAPEUTIC RESPONSE.
Keywords
INFLAMMATORY BOWEL DISEASE C-REACTIVE PROTEIN ERYTHROCYTE
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