INTEROBSERVER VARIABILITY IN PLACENTAL HISTOPATHOLOGY DIAGNOSIS OF INFLAMMATORY LESIONS- A STATISTICAL EXPERIMENT

THE WORLDWIDE TREND FOR MEDICAL PRACTICE, IN GENERAL, AND FOR HISTOPATHOLOGICAL LESIONS DIAGNOSIS, IN PARTICULAR, TURNS IN FAVOR FOR PROTOCOL USE, AS IN MANY COUNTRIES AND S PECIALTIES, THESE ARE NOT WELL IMPLEMENTED. OUR AIM REFERS TO AN EXPERIMENT THAT INVOLVED FIVE AVERAGE EXPERIENCED OBSERVERS THAT EXAMINED 10 PLACENTAS WITH CHORIOAMNIONITIS, 4 ACUTE CASES AND 6 CHRONIC CASES. THEY HAD TO ISSUE THE DEGREE OF EXTENT OF BASI C LESIONS: HYALINE DEPOSITION, INFLAMMATION, FIBROSIS, NECROSIS AND HYPEREMIA. THE INSTRUMENT USED WAS A LIKERT SCALE WITH FIVE DEGREES OF INTENSITY. KAPPA STATISTICAL CALCULATIONS PROVED A SLIGHT DIFFERENCE BETWEEN THE FIVE EXAMINATORS IN REGARDING THE APPRECIATION OF LESION SEVERITY. THE INTEROBSERVER AGREMEENT WAS BETWEEN 0.04 TO 0.14 WITH HIGHER CONSISTENCY TOWARD OBVIOUS LESIONS WITH ALPHA VALUES FROM 0.61 TO 0.81.THUS SHOWING THE NECESSITY FOR A FAR PRECISE DIAGNOSIS PROTOCOL TO BE IMPLEMENTED , AS THE LESIONS IN CHORIOAMNIONITIS PLACENTA MA BE VERY DIFFICULT TO APRECIATE.

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