CARDIOVASCULAR COMORBIDITIES IN PARKINSON DISEASE PATIENTS

PARKINSON'S DISEASE (PD) IS THE SECOND MOST COMMON NEURODEGENERATIVE DISORDERS, AND THESE PATIENTS CAN HAVE A WIDE RANGE OF CARDIOVASCULAR COMORBIDITIES THAT INFLUENCE THE CLINICAL COURSE OF THE DISEASE2. A CLINICAL, CROSS -SECTIONAL, OBSERVATIONAL STUDY HAS BEEN PERFORMED ON A GROUP OF 86 CONSECUTIVE PATIENTS WITH IDIOPATHIC PARKINSON’S DISEASE. THE PATIENTS HAVE BEEN INTERVIEWED ABOUT DISEASE DURATION, ASSOCIATED MEDICAL CONDITIONS AND CURRENT MEDICATIONS. THE MOST PREVALENT CARDIOVASCULAR COMORBIDITIES IDENTIFIED IN OUR STUDY POPULATION WERE: ARTERIAL HYPERTENSION (48.83%, 95%CI 38.27 -59.39), CHRONIC CARDIAC ISCHEMIC DISEASE 40.69%, 95%CI 30.31 -51.07). DATA ANALYSIS SHOWED NO STATISTICALLY SIGNIFICANT DIFFERENCE BETWEEN MALES AND FEMALES REGARDING THE PREVALENCE RATES FOR BOTH ARTERIAL HYPERTENSION (P=0.5) AND CHRONIC ISCHEMIC HEART DISEASE (P=0.5). COMPARING THE PREVALENCE VALUES IN ROMANIAN GENERAL POPULATION FOR THESE TWO IMPORTANT CARDIO-VASCULAR DISORDERS WITH OUR STUDY RESULTS LEADS TO THE CONCLUSION THAT ARTERIAL HYPERTENSION HAS BEEN FOUN D NOT STATISTICALLY SIGNIFICANT MORE PREVALENT IN STUDIED ROMANIAN PARKINSONIAN PATIENTS THAN IN GENERAL POPULATION (P=0.49) AND THAT CHRONIC ISCHEMIC HEART DISEASE WERE STATISTICALLY SIGNIFICANT MORE PREVALENT IN STUDIED ROMANIAN PARKINSONIAN PATIENTS THAN IN GENERAL POPULATION (P<0.0001).

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