THE ROLE OF ALUMINUM IN THE SYMPTOMATOLOGY OF ATTENTION DEFICIT HYPERACTIVITY DISORDER CHILDREN
Corresponding author:
[email protected]
Accepted
28 March 2026
Available Online
15 June 2018
Abstract
ALUMINUM IS A CHEMICAL ELEMENT ATOMIC NUMBER 13. IT IS WHITE -SILVER, INSOLUBLE IN WATER UNDER NORMAL CONDITIONS. DESPITE ITS NATURAL ABUND ANCE, ALUMINUM HAS NO KNOWN BIOLOGY FUNCTION. IT IS A TOXIC RESIDUE, ALUMINUM SULPHATE HAVING AN LD50 OF 6207 MG/KG BODY, CORRESPONDING TO 500 GRAMS PER 80 KG PERSON. EXTREMELY ACUTE TOXICITY WITHOUT HARM TO HEALTH IS OF INTEREST IN VIEW OF THE WIDESPREAD OCCURRENCE OF THE ELEMENT IN THE ENVIRONMENT AND IN TRADE 7. TOXICITY CAN BE TRACKED AFTER DEPOSITION INTO THE BONES AND THE CENTRAL NERVOUS SYSTEM AND IS PARTICULARLY HIGH IN PATIENTS WITH RENAL INSUFFICIENCY. BECAUSE ALUMINUM COMPETES WITH CALCIUM FOR ABSORPTION, INCREASED ALUMINA CAN CONTRIBUTE TO OSTEOPENIA, PRETERM AND GROWTH RETARDATION. IN VERY HIGH DOSES, ALUMINUM CAN CAUSE NEURO TOXICITY ASSOCIATED WITH ALTERED FUNCTION OF THE BLOOD-BRAIN BARRIER8. OBJECTIVES THE STUDY PROPOSES A COMPARISON OF THE CONCENTRATION OF URINE ALUMINUM HARVESTED FROM A GROUP OF CHILDREN DIAGNOSED WITH ADHD VERSUS THE NORMAL “CHILDREN'S HOMES SOS CHILDREN'S VILLAGES” AND THE ANALYSIS OF THE INFLUENCE OF THE SEX OF THE CHILDREN ON URINE CONCENTRATIONS OF ALUMINUM.
Keywords
ADHD
URINE
ALUMINIUM
GF-AAS
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[1]
Type of injection Auto dilution
[2]
Modul de calibrare Concentraţie
[3]
Type of measurement Height peak
[4]
Standard replicates 2
[5]
Sample replicates 2
[6]
Smoothing 9
[7]
Wavelength 309.3 nm
[8]
Slit width 0.2 nm
[9]
Lamp current 10 mA
[10]
Background correction Da
[11]
Standard 1 20 μg/l
[12]
Standard 2 50 g/dl
[13]
Standard 3 100 g/dl
[14]
Recalibration rate 10
[15]
Reslope rate 1
[16]
Concentration decimal places 2
[17]
Calibration algorithm New Rational
[18]
Replicate % RSD limit 10%
[19]
Correlation coeficient limit 0.998
[20]
Required detection limit 1 μg/L
[21]
Instrument detection limit 0.6 μg/l
[22]
Injected volume 15 l
[23]
Sample volume 10 l
[24]
Dilution coeficient 2 Table 2. General parameters for graphite furnace. PARAMETER STEP 1 STEP 2 STEP 3 STEP 4 STEP 5 STEP 6 STEP 7 STEP 8 Temp. (0C) 40 85 85 95 120 120 1000 1000 Time (s) 2 5 5 40 40 4 6 2 Gases N N N N N Ar Ar Ar Flow (mL/min) 3 3 3 3 3 3 3 0 Read - - - - - - - - Store - - - - - - - YES PARAMETRER STEP 9 STEP STEP STEP STEP STEP Temp. (0C) 2700 2700 3000 3000 40 40 Time (s) 2 1 0.1 2 22.3 3 Gases Ar Ar N N N N Flow (mL/min) 0 0 3.1 3.1 3 0 Read YES YES - - - - Store YES YES - - - -