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Research Articles Issue 2 · 2018 · pp. 186–193 · Issue page

GLUCOCORTICOID THERAPY IN PATIENTS WITH RHEUMATOID ARTHRITIS – A CAUSE OF HYPERTENSION

CR
Cristina Gabriela ENE1
CR
Cristina Florina OLTEANU2
MI
Mihaela VLADU3
DI
Diana CLENCIU4
GA
Gabriela Nicoleta MĂTUȘOIU5
LU
Lucrețiu RADU6
RO
Romeo POPA7
TI
Tiberiu Stefăniță ȚENEA-COJAN8
ST
Stefăniță ȚENEA-COJAN8 Raluca Elena BOȚOAGĂ9
1 PhD student , Department of Pharmacology, University of Medicine and Pharmacy of Craiova
2 Emergency Clinical County Hospital of Craiova, Department of Internal Medicine
3 Department of Metabolism and Nutrition Diseases, Faculty of Medicine, University of Medicine and Pharmacy of Craiova
4 Department of Metabolism and Nutrition Diseases, Municipal Clinical Hospital “Filantropia”
5 Emergency Clinical County Hospital of Craiova, Department of Internal Medicine
6 Department of Hygiene, Faculty of Medicine, University of Medicine and Pharmacy of Craiova
7 PhD Student, Department of Pharmacology, University of Medicine and Pharmacy of Craiova
8 Department of Surgery, Faculty of Medicine, University of Medicine and Pharmacy of Craiova
9 Department of Hematology, Municipal Clinical Hospital “Filantropia”
Accepted 28 March 2026
Available Online 15 November 2018
Abstract
RHEUMATOID ARTHRITIS (RA) IS AN AUTOIMMUNE DISEASE THAT AFFECTS ESPECIALLY THE JOINTS BUT IT’S AUTOIMMUNE CHARACTER IS BEST SEEN IN ITS SYSTEMIC AFFECTION. PATIENTS WITH RA ARE WELL KNOWN TO HAVE AN IMPORTANT RISK OF MORBIDITY AND MORTALITY FROM CARDIOVASCULAR DISEASE (CVD). NOWADAYS, GLUCOCORTICOIDS (GDS) ARE USED IN RHEUMATOLOGY AS “BRIDGE THERAPY” WHILE WAITING FOR ONSET OF ACTION OF DISEASE-MODIFYING ANTIRHEUMATIC DRUGS (DMARDS) , OR FOR DISEASE FLARES 10. NUMEROUS STUDY SUGGEST THAT THE USE OF GCS ALO NG WITH STANDARD THERAPY CAN SUBSTANTIALLY REDUCE THE PROGRESSION OF EROSION IN RA 11
Keywords
GLUCOCORTICOIDS RHEUMATOID ARTHRITIS HYPERTENSION CARDIOVASCULAR
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