HYPERTRIGLYCERIDAEMIC PANCREATITIS AND DIABETIC KETOACIDOSIS
Received
04 July 2021
Revised
19 September 2021
Accepted
16 October 2021
Available Online
15 November 2021
Abstract
ACUTE PANCREA TITIS IS AN INFLAMMATORY CONDITION OF THE PANCREAS WITH MULTIPLE ETIOLOGIES. HYPERTRIGLYCERIDAEMIC PANCREATITIS (HTG-AP) IS NOT A COMMON CAUSE OF AP BUT IS ASOCIATED WITH A INCREASED RATE OF COMPLICATIONS. PATIENTS WITH DIABET ES MELLITUS ARE AT INCREASED RISK OF AP. THE ASSOCIATIN BETWEEN HYPERTRIGLYCERIDAEMIA, KETOACIDOSIS AND AP IS RARE. THE TREATMENT OF THIS TYPE OF PANCREATITIS IS NOT WELL ESTABLISHED IN CURRENT GUIDELINES, SPECIFIC TERAPEUTIC MEASUREMENTS INCLUDE HEPARIN, INSULIN TREATMENT, PLASMAPHER ESIS, COMBINED BLOOD PURIFICATION THERAPY, HIGH-VOLUME HEMOFILTRATION AND HEMOPERFUSION. WE REPORTED TWO CASES OF HYPERTRIGLYCERIDAEMIA (HTG) INDUCED AP, IN PACIENTS WITH UNCONTROLLED TYPE 2 DIABETES MELLITUS AND KETOACIDOSIS ONE TREATED WITH INSULIN IN FUSION AND ANOTHER TREATED WITH INSULIN INFUSION AND PLASMAPHERESIS. BOTH CASES WERE SUCCESSFULLY MANAGED WITH SPECIFIC MEASURES AND SUPPORTIVE CARE.
Keywords
ACUTE PANCREATITIS
HYPERTRIGLYCERIDAEMIA
DIABETIC KETOACIDOSIS
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