ETIOLOGY AND DRUG SUSCEPTIBILITY OF BACTERIAL
Corresponding author:
[email protected]
Accepted
28 March 2026
Available Online
15 November 2016
Abstract
RECOGNITION OF THE UNIQUE MICROBIOLOGY OF CHRONIC SINUSITIS AND ANTIMICROBIAL SUSCEPTIBILITY IS VERY IMPORTANT FOR SELECTING ANTIMICROBIAL THERAPY. THE AIM OF THIS STUDY WAS TO DETERMINE THE ETIOLOGY AND ANTIBIOTIC SUSCEPTIBILITY OF THE BACTERIA CAUSING ACUTE AND CHRONIC SINUSITIS. THE STUDY GROUP INCLUDED 111 BACTERIAL STRAINS ISOLATED FROM SINUS PUNCTURE OBTAINED FROM 150 PATIENTS HOSPITALIZED AT COUNTY CLINICAL EMERGENCY HOSPITAL, CRAIO VA, ROMANIA FROM 01.01.2014 TO 01.01.2016. THE ISOLATES WERE IDENTIFIED BY CONVENTIONAL MICROBIOLOGICAL PROCEDURES. ANTIMICROBIAL SUSCEPTIBILITY TESTING WAS DETERMINED BY DISK DIFFUSION METHOD ON MUELLER-HINTON AGAR (BIOMERIEUX, USA) FOLLOWING CRITERIA AS RECOMMENDED BY THE CLINICAL AND LABORATORY STANDARDS INSTITUTE (CLSI, DENVER, USA). THE PREVALENCE OF BACTERIAL AGENTS WAS: PSEUDOMONAS AERUGINOSA STRAINS 24 (13,11%), STAPHYLOCOCCUS STRAINS FOR S.AUREUS AND S. EPIDERMIDIS 26 (14,20%) RESPECTIVELY 47 (25, 68%) AND ACINETOBACTER BAUMANNII STRAINS 14 (7,65%). OF ALL P. AERUGINOSA CULTURED, 83.33% WERE RESISTANT TO CIPROFLOXACIN AND 97.92% SENSITIVITY TO COLISTIN. OF THE 26 STRAINS OF STAPHYLOCOCCUS AUREUS , 10 (38,46%) WERE MRSA
Keywords
CHRONIC SINUSITIS
ACUTE SINUSITIS
BACTERIA
ANTIBIOTIC RESISTANCE
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References
[1]
Ashworth MA, Charlton J, Ballard K, et al. Variations in antibiotic prescribing and consultation rates for acute respiratory infection in UK general practices 1995–2000. Br J Gen Pract 2005;55:603–8.
[2]
Gonzales R, Steiner JF, Lum A , et al. Decreasing antibiotic use in ambulatory practice: impact of a multidimensional intervention on the treatment of uncomplicated acute bronchitis in adults. JAMA 1999;281:1512–19.
[3]
Institut fur Medizinische Statistik. Verordnungsindex Pharmazeutika 2003.
[4]
Groupe d’Etude des Sinusites Infectieuses. Current approaches to communityacquir ed acute maxillary rhinosinusitis or sinusitis in France and literature review. Rhinol 2001;17(Supp1):1 –38.
[5]
Osguthorpe JD, Hadley JA. Rhinoinusitis. Current concepts in evaluation and management. Otolaryngology for the internist. Med Clin N Am 1999;83:27–41.
[6]
Ray NF, Baraniuk IN, Thamer M , et al. Healthcare expenditures for sinusitis in 1996: contributions of asthma, rhinitis, and other airway disorders. J Allergy ClinImmunol 1999;103:408 –14.
[7]
Schappert SM. Ambulatory care visits to physician offices, hospital outpatient departments, and emergency departments: United States, 1996. Vital Health Stat 1998;134:1–37.
[8]
Farajzadeh Sheikh A, Ahmadi K, Nikakhlagh S. Detection of Streptococcus pneumoniae and Moraxella catarrhalis in patients with paranasal chronic sinusitis by polymerase chain reaction method. J Chin Med Assoc. 2016 Aug;79(8):440-4. doi: 10.1016/j.jcma.2016.03.002. Epub 2016 Jun 6.[pubmed]
[9]
Brook I. Microbiology of chronic rhinosinusitis. Eur J Clin Microbiol Infect Dis. 2016 Jul;35(7):1059 -68. doi: 10.1007/s10096-016-2640-x. Epub 2016 Apr 16.[pubmed]
[10]
Boase S, Foreman A, Cleland E , et al. The microbiome of chronic rhinosinusitis: culture, molecular diagnostics and biofilm detection. BMC Infect Dis 2013; 13: 210.
[11]
Hsu J, Lanza DC, Kennedy DW. Antimicrobial resistance in bacterial chronic sinusitis. Am J Rhinol 1998; 12: 243-8.
[12]
Eslami G, Salehifar E, Behbudi M, Rezai MS . Rational Use of Amikacin in Buali -Sina Hospital in Sari, 2011. J Mazandaran Univ Med Sci 2013; 23: 2-9.
[13]
Solares CA, Batra PS, Hall GS, Citardi MJ . Treatment of chronic rhinosinusitis exacerbations due to methicillin-resistant Staphylococcus aureus with mupirocin irrigations. Am J Otolaryngol 2006; 27: 161 -5.
[14]
Rahmati M, Mohebi S, Shahmohammadi S, Rezai M. Fluticasone nasal spray as an adjunct to Amoxicillin for acute sinusitis in children: a randomized controlled trial. Eur Rev Med Pharmacol Sci 2013; 17: 3068-72.
[15]
ClSI. Performance Standards for Antimicrobial Susceptibility Testing; Twenty -Third Informational Supplement. M100 -S23. Clinical & Laboratory Standards Institute 2013. https://books.google.com /books?id=ARhelwEACAAJ
[16]
United States Department of Health and Human Services.National health survey. Prevalence of selected chronic conditions,United States, 1983–85. Hyattsville, Md: US Departmentof Health and Human Servic es, 1987.
[17]
Adelglass J, Jones TM, Ruoff G, Kahn J, Wiesinger B, Reilly -Gauvin K , et al. A multicenter, investigator-blinded, randomized comparison of oral levofloxacin and oral clarithromycin in the treatment of acute bacterial sinusitis. Pharmacotherapy 1998;18:1255-63.
[18]
Kaliner MA, Osguthorpe JD, Fireman P, Anon J, Georgitis J, Davis M, et al. Sinusitis: bench to bedside. Current findings, future directions. J Allergy Clin Immunol 1997;99(suppl): S829 -S848.
[19]
Raeisi J, Saifi M, Pourshafie MR, Asadi Karam MR, Mohajerani HR. Rapid detection of methicillin - resistant staphylococcus aureus isolates by turanose fermentation method. Jundishapur J Microbial 2015; 8: e21198.
[20]
Manarey CRA, Anand VK, Huang C . Incidence of methicillin resistant staphylococcus aureus caus ing chronic rhinosinusitis. Laryngoscope 2004; 114: 939-41.
[21]
Brook I, Foote PA, Hausfeld JN . Increase in the frequency of recovery of meticillin -resistant Staphylococcus aureus in acute and chronic maxillary sinusitis. J Med Microbiol. 2008;57:1015[PubMed]
[22]
Zhanel GG1, Fontaine S, Adam H, Schurek K, Mayer M, Noreddin AM, Gin AS, Rubinstein E, Hoban DJ. A Review of New Fluoroquinolones : Focus on their Use in Respiratory Tract Infections. Treat Respir Med. 2006;5(6):437-65. [PubMed] November 2016
[23]
ORL J Otorhinolaryngol Relat Spec. 2009;71(5):263 -7. doi: 10.1159/000242428. Epub 2009 Sep 30. Fluoroquinolone-resistant Pseudomonas aeruginosa in chronic rhinosinusitis. Guss J1, Abuzeid WM, Doghramji L, Edelstein PH, Chiu AG.[pubmed]
[24]
Braz J Otorhinolaryngol. 2012 Jul-Aug;78(4):35-41. The role of maxillary sinus puncture on the diagnosis and treatment of patients with hospital-acquired rhinosinusitis. Mendes Neto JA1, Guerreiro VM, Hirai ER, Kosugi EM, Santos Rde P, Gregório LC.
[25]
Motaouakkil, S., B. Charra, A. Hachimi, H. Nejmi, A. Benslama, N. Elmdaghri, H. Belabbes, and M. Benbachir. 2006. Colistin and rifampicin in the treatment of nosocomial infections from multiresistant Acinetobacter baumannii.J. Infect. 53:274–278.