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Research Articles Supplement 2 · 2018 · pp. 66–80 · Issue page

THE THERAPEUTIC MANAGEMENT IN COLONIC DIVERTICULAR DISEASE – A REVIEW

SI
Simona BOBIC1
BO
Bogdan SOCEA2
CA
Camelia DIACONU3
OV
Ovidiu BRATU4
DR
Dragoş MARCU5
MA
Maria MANEA6
ŞE
Şerban BERTEŞTEANU7
TI
Tiberiu Stefanita TENEA COJAN8
VL
Vlad-Dumitru BĂLEANU9
VL
Vlad Denis CONSTANTIN10
1 University of Medicine and Pharmacy Carol Davila, 8 Eroii Sanitari Str, 050474, Bucharest, Romania; "Sf. Pantelimon" Emergency Clinical Hospital, General Surgery Department, 340 Sos. Pantelimon, 021659, Bucharest, Romania
2 University of Medicine and Pharmacy Carol Davila, 8 Eroii Sanitari Str, 050474, Bucharest, Romania; "Sf. Pantelimon" Emergency Clinical Hospital, General Surgery Department, 340 Sos. Pantelimon, 021659, Bucharest, Romania
3 University of Medicine and Pharmacy Carol Davila, 8 Eroii Sanitari Str, 050474, Bucharest, Romania; Emergency Clinical Hospital of Bucharest, Internal Medicine Department, 8 Calea Floreasca, 014461, Bucharest, Romania
4 University of Medicine and Pharmacy Carol Davila, 8 Eroii Sanitari Str, 050474, Bucharest, Romania; Carol Davila University Emergency Central Emergency Military Hospital, 88 Mircea Vulcanescu Str, 010825, Bucharest, Romania; Academy of Romanian Scientists, 54 Splaiul Independentei, 050085, Bucharest, Romania
5 University of Medicine and Pharmacy Carol Davila, 8 Eroii Sanitari Str, 050474, Bucharest, Romania; Carol Davila University Emergency Central Emergency Military Hospital, 88 Mircea Vulcanescu Str, 010825, Bucharest, Romania
6 Carol Davila University Emergency Central Emergency Military Hospital, 88 Mircea Vulcanescu Str, 010825, Bucharest, Romania
7 University of Medicine and Pharmacy Carol Davila, 8 Eroii Sanitari Str, 050474, Bucharest, Romania; ENT Clinic, Colţea Clinical Hospital, 1 Bd. IC Brătianu, 030171, Bucharest, Romania
8 University of Medicine and Pharmacy of Craiova, 2 Petru Rares Str., 200349, Craiova, Romania
9 "Sf. Pantelimon" Emergency Clinical Hospital, General Surgery Department, 340 Sos. Pantelimon, 021659, Bucharest, Romania; University of Medicine and Pharmacy of Craiova, 2 Petru Rares Str., 200349, Craiova, Romania
10 University of Medicine and Pharmacy Carol Davila, 8 Eroii Sanitari Str, 050474, Bucharest, Romania; "Sf. Pantelimon" Emergency Clinical Hospital, General Surgery Department, 340 Sos. Pantelimon, 021659, Bucharest, Romania
Accepted 28 March 2026
Available Online 15 September 2018
Abstract
INTRODUCTION. THE DIVERTICULAR DISEASE REPRESENTS A COMMON PATHOLOGY IN DEVELOPED OR DEVELOPING COUNTRIES. FOR ABOUT 80% OF PATIENTS THE DISEASE IS ASYMPTOMATIC (DIVERTICULOSIS), 20% DEVELOPING NON-SPECIFIC DIGESTIVE SYMPTOMS (UNCOMPLICATED SYMPTOMATIC DIVERTICULAR DISEASE) OR CMPLICATIONS, SUCH AS ACUTE DIVERTICULITIS. MATERIAL AND METHOD. THE AIM OF THE RESEARCH IS TO PRESENT THE THERAPEUTICAL APPROACH IN COLONIC DIVERTICULOSIS, UNCOMPLICATED SYMPTOMATIC DIVERTICULAR DISEASE AND ACUTE DIVERTICULITIS, A REVIEW OF THE RECENT MEDICAL LITERATURE BEING MADE TO SUPPORT THE INFORMATION PROVIDED. RESULTS. THE DATA AVAILABLE FROM THE LAST 10 YEARS REGARDING THE SUBJECT HAVE BEEN ANALYZED. OVER THE PAST 5 YEARS 6 DIFFERENT THERAPEUTIC GUIDELINES FOR THE COLONIC DIVERTICULAR DISEASE HAVE BEEN REGISTERED. THERE ARE NO CLEAR INDICATIONS REGARDING THE MEDICAL TREATMENT IN ASYMPTOMATIC COLONIC DIVERTICULOSIS, THE INDICATIONS BEING ALSO LIMITED IN THE CASE OF LOWERING THE RISK OF DIVERTICULOSIS BY INCREASING THE FIBER INTAKE. THERE IS NOT YET A THERAPEUTIC STANDARD IN ASYMPTOMATIC DIVERTICULAR DISEASE, VARIOUS THERAPEUTIC STRATEGIES WITH FIBERS, PROBIOTICS, RIFAXIMIN OR MESALAZINE BEING TAKEN INTO CONSIDERATION. AN AGREEMENT HAS BEEN REACHED IN THE TREATMENT OF THE ACUTE DIVERTICULITIS, THE LATEST GUIDELINES DEMONSTRATING THE FACT THAT ANTIBIOTICS CAN BE ADMINISTERED ONLY IN CAREFULLY SELECTED CASES, AVOIDING THEIR ROUTINE USE. THE RESULTS OF THE VARIOUS STUDIES REGARDING THE PRIMARY OR SECONDARY PROPHYLAXIS IN ACUTE DIVERTICULITIS AND THE EFFICACY OF RIFAXIMIN OR MESALAZINE ARE HETEROGENOUS.
Keywords
ACUTE DIVERTICULITIS DIVERTICULOSIS UNCOMPLICATED SYMPTOMATIC
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