VILLOUS HYPERMUCINOUS APPEARENCE IN LONGSTANDING INFLAMMATORY BOWEL DISEASE: A CASE REPORT AND REVIEW OF LITERATURE
Corresponding author:
[email protected]
Received
09 April 2020
Revised
-
Accepted
15 May 2020
Available Online
02 June 2020
Abstract
THE CORRECT EXAMINATION, BY AN ANATOMOPATHOLOGIST WITH EXPERTISE IN INFLAMMATORY BOWEL DISEASES, OF BIOPSIES OR RESECTION PIECES IS OF OVERWHELMING IMPORTANCE FOR ESTABLISHING THE DEFINITE DIAGNOSIS, BUT ALSO CONSIDERING MANAGEMENT STRATEGIES AND SUBSEQUENT SURVEILLANCE OF THE PATIENT, G IVEN THE FACT THAT THERE IS A POSSIBILITY OF PROGRESSION OF DYSPASTIC LESIONS TO ADENOCARCINOMA , IN THE LONGSTANDING DISEASE. THE RISK OF COLORECTAL CANCER IS CUMULATIVE, ESPECIALLY IN ULCERATI VE COLITIS, AS THE YEARS PASS , SO BIOPSIES FROM SUSPICIOUS ARE A SHOULD BE TAKEN, WHENEVER NEEDED . REGULAR ENDOSCOPIC FOLLOW-UP IS RECCOMENDED BY THE NTERNATIONAL GUIDELINES AND SHOULD BE TAILORED TO EACH INDIVIDUAL, TAKING INTO ACCOUNT THE RISK FACTORS, THE DETECTION OF DYSPALSIA BEING THE MOST IMPORTANT GOAL OF SURV EILLANCE COLONOSCOPY . EARLY IDENTIFICATION OF DYSPLASIA (MACROSCOPICALLY VISIBLE OR NOT) IS THE CORNERSTONE OF REDUCING THE RISK OF COLORECTAL CANCER. IN RECENT YEARS, SEVERAL NEW TYPES OF UNCONVENTIONAL DYSPLASIA HAVE BEEN RECOGNIZED, BUT EXACT MORPHOLOGI C CRITERIA ARE REQUIRED. OF ALL PATTERNS ENCOUNTERED, THE HYPERMUCINOUS DYSPLASIA HAS BEEN THE MOST COMMONLY DETECTED AND DESCRIBED . THE ASSOCIATION WITH CLASSIC DYSPLASIA OR EVEN COLORECTAL CANCER IS STILL NOT ENOUGH STUDIED SO FAR.
Keywords
INFLAMMATORY BOWEL DISEASE
HISTOPATHOLOGY
UNCONVENTIONAL
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